Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 SusceptibilityMutation ORPHANET The prevalence and characteristics of microalbuminuria in the general population: a cross-sectional study. 23830507

2013
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 SusceptibilityMutation ORPHANET Our findings indicate that IL12B plays a fundamental role on the pathophysiology of TAK in combination with HLA-B(∗)52:01 and that common autoimmune mechanisms underlie the pathology of TAK and other autoimmune disorders such as psoriasis and inflammatory bowel diseases in which IL12B is involved as a genetic predisposing factor. 23830516

2013
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.400 SusceptibilityMutation ORPHANET The prevalence and characteristics of microalbuminuria in the general population: a cross-sectional study. 23830507

2013
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.400 SusceptibilityMutation ORPHANET Our findings indicate that IL12B plays a fundamental role on the pathophysiology of TAK in combination with HLA-B(∗)52:01 and that common autoimmune mechanisms underlie the pathology of TAK and other autoimmune disorders such as psoriasis and inflammatory bowel diseases in which IL12B is involved as a genetic predisposing factor. 23830516

2013
Entrez Id: 6945
Gene Symbol: MLX
MLX
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.340 SusceptibilityMutation ORPHANET Two susceptibility loci to Takayasu arteritis reveal a synergistic role of the IL12B and HLA-B regions in a Japanese population. 23830516

2013
Entrez Id: 6945
Gene Symbol: MLX
MLX
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.340 SusceptibilityMutation ORPHANET The prevalence and characteristics of microalbuminuria in the general population: a cross-sectional study. 23830507

2013
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 Biomarker LHGDN In the present work, we analyzed the sequence of HLA-B alleles in 26 TA patients and 62 healthy controls. 15585327

2005
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 Biomarker LHGDN This preliminary study suggests a difference in the distribution of the residues 63 and 67 of the HLA-B alleles in patients with TA and TB. 18646257

2008
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 GeneticVariation LHGDN In spite of the loose clinical relationship between TA and Tb, we did not detected any genetic relationship between them when the HLA-B alleles were analyzed in these groups of patients. 17462513

2007
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.040 GeneticVariation LHGDN HLA alleles in Korean patients with Takayasu arteritis. 17428358

2007
Entrez Id: 6965
Gene Symbol: TRG
TRG
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 AlteredExpression LHGDN T-cell receptor repertoire of circulating gamma delta T-cells in Takayasu's arteritis. 16307908

2006
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 Biomarker LHGDN MMP-2 levels were higher in patients with TA than in controls, but no correlation was found between serum MMP-2 and disease activity score. 12952836

2003
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 AlteredExpression LHGDN P-selectin expression, but not GPIIb/IIIa activation, is enhanced in the inflammatory stage of Takayasu's arteritis. 16636497

2006
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 Biomarker LHGDN Circulating levels of MMP-2, MMP-3, and MMP-9 were determined by ELISA in all patients with TA and controls. 12952836

2003
Entrez Id: 8744
Gene Symbol: TNFSF9
TNFSF9
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 Biomarker LHGDN Our findings strongly suggest that 4-1BB/4-1BBL and Fas/FasL pathways play important roles in vascular injury in Takayasu's arteritis. 14752253

2004
Entrez Id: 6403
Gene Symbol: SELP
SELP
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 AlteredExpression LHGDN P-selectin may play a significant role in the inflammatory and thrombotic responses associated with intractable TA, presumably by inducing platelet-leukocyte interactions. 16636497

2006
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 GeneticVariation LHGDN Takayasu arteritis with high titre of antiphospholipid antibodies and MTHFR Polymorphism. 16133896

2005
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 Biomarker LHGDN Circulating levels of MMP-2, MMP-3, and MMP-9 were determined by ELISA in all patients with TA and controls. 12952836

2003
Entrez Id: 6964
Gene Symbol: TRD
TRD
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 Biomarker LHGDN T-cell receptor repertoire of circulating gamma delta T-cells in Takayasu's arteritis. 16307908

2006
Entrez Id: 3674
Gene Symbol: ITGA2B
ITGA2B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 AlteredExpression LHGDN P-selectin expression, but not activated GPIIb/IIIa, is enhanced in ADP-activated platelets from patients in the inflammatory stage of TA. 16636497

2006
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 GeneticVariation GWASCAT Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. 30498034

2018
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.500 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.200 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
Entrez Id: 6203
Gene Symbol: RPS9
RPS9
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.110 GeneticVariation GWASCAT Identification of Susceptibility Loci in IL6, RPS9/LILRB3, and an Intergenic Locus on Chromosome 21q22 in Takayasu Arteritis in a Genome-Wide Association Study. 25604533

2015
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.100 GeneticVariation GWASCAT Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis. 30498034

2018